Associate Professor David McMillan completed his PhD at the University of Wollongong and completed post-doctoral studies at the Queensland Institute for Medical Research and the German Research Centre for Biotechnology, Braunschweig, Germany. He was appointed Senior Research Fellow at UniSC in 2013.

Research interests

The major research interests of my group are the study and prevention of Streptococcus pyogenes infections and discovery of novel antibiotics.

S. pyogenes infection results in half a million deaths each year. The bacterium is one of the leading bacterial killers of humans for which no vaccine is available. Research in this theme is focused on the:

• development and evaluation of novel group A streptococcal vaccines
• understanding the genetic basis of group A streptococcal disease
• population genetics of streptococci.

The emergence and global expansion of antibiotic resistant bacteria is having a major impact on our ability to treat once preventable diseases. For some bacterial strains, failures in ‘antibiotics of last resort’ have been reported. Research in this theme is focused on:

• identification and testing novel antibiotic compounds from natural sources
• characterisation of antimicrobial resistance mechanisms.

Honours and postgraduate projects

Our research group has research projects available in all above themes. Please contact Dr David McMillan for more information.