Associate Professor Joanne Macdonald
BSc Qld, BSc Hons Qld, PhD Qld
Associate Professor, Molecular Engineering
Deputy Director, Centre for Bioinnovation
School of Science, Technology and Engineering
Email: jmacdon1@usc.edu.au
Telephone: +61 7 5456 5944
Location: Sunshine Coast, Building I, Level 1, Room 14A (SD-I-1.14A)
Dr Joanne Macdonald’s research applies molecular engineering principles to provide novel solutions for industry and consumers. She previously co-developed a computer from DNA molecules that can play tic-tac-toe interactively against a human opponent, and is now developing biosensors that can display text without requiring electricity, because the molecules themselves power the device. With a background in virology, she is applying her biosensor technology for the diagnosis of deadly pathogens, including Hendra and Ebola virus, as well as mosquito transmitted pathogens such as Malaria, Dengue virus, and Chikungunya viruses, and water pathogens such as Adenovirus.
Dr Macdonald also has a strong industry focus to translate research ideas into products. She is currently the UniSC academic lead for the Food and Agribusiness/Turbine food and beverage contract manufacturing facility being constructed at Caloundra. She is also working with industry to improve point of care detection of pathogens for both human and animal diseases. Previously, she co-invented an anti-cocaine therapeutic enzyme that has completed Phase II clinical trials for treatment of cocaine overdose. Other previous projects include the development of antidotes for the treatment of nerve agents and pesticide poisoning, and the investigation of the structure and strength of spider silk as an advanced material.
Dr Macdonald gained international recognition from Gates Open Research and was invited to speak to a blog for world mosquito day “Enhancing dengue virus surveillance and control with new rapid tests.” Joanne Macdonald, Nina Pollak and Madeeha Ahmed 17 August 2023.
Research
Teaching and supervision
Teaching
Teaching Summary
Potential research projects for HDR and Honours students
- Improved rapid point-of-care diagnostics
Current limitations in rapid point-of-care diagnostics prevent sensitive analysis of multiple types of specimens. This project involves research into state-of-the art biosensor development and application to detection of genetic markers and pathogens.
Dates – ongoing
Professional
Awards and memberships
Awards
- Project Leadership Awards: DMTC 2023 Annual Conference, Canberra, ACT, 18 April 2023
The DMTC Ltd, which funded the research, said Joanne received the award because it was clear the value that stakeholders placed on her passion for research, her respect for her colleagues and her leading by example of a highly diligent research group
- High commendation award: Health Security Systems Australia (a division of DMTC), in partnership with BioCifer Pty Ltd, CSIRO and academic partners of the University of the Sunshine Coast and The University of Queensland, Land Forces 2022 Innovation Awards, Brisbane, QLD, 4 October 2022
- Rose Anne-Kelso Commemorative Award, Life Sciences Queensland, October 2016
Professional memberships
- Australian Society for Microbiology (ASM)
- Australian Society for Microbiology and Biochemistry (ASBMB)
- International Society for Infectious Diseases (ISID)
- Australian Nanotechnology Network (ANN)